Everglades National Park, easily accessible from any of the Key Largo vacation rentals, owns the credit of being the biggest subtropical wilderness in the U.S. It has been accredited as a World Heritage Site and International Biosphere Reserve as it is the home to several endangered species. Also, do not miss on visiting John Pennekamp Coral Reef State Park and Dagny Johnson Key Largo Hammock Botanical State Park. The underwater treasures of Florida Keys National Marine Sanctuary are surely going to awe you. Jacobs Aquatic Center is another interesting site that features a competition pool, water park, "spray" gym, and much more. The spectacular sunset view over Florida Bay is a not-to-be-missed sight. You can also plan for a weekend getaway from here to the nearby city of Miami. For accommodation, there are several sophisticated Miami vacation rentals. Alternatively, you can also put up at one of the Miami Beach vacation rentals to conveniently explore the city of Miami.

Shopping in Key Largo can be a really delightful experience as there are plenty of shops selling t-shirts, gifts, jewelry, water-sports equipment, etc. Booking Key Largo FL vacation rentals will be worthwhile during the annual 'Key Largo Food and Wine Festival' that is celebrated for nine consecutive days. Also, this island is a gourmet's delight. There are a host of restaurants serving everything from traditional local fare to international delicacies.